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Respiratory Syndrome Linked Pathogens Multiplex Detection and characterization – ReSynPlex
Respiratory infections are a major threat to human health. According to WHO, respiratory infections are the cause of 60 % of deaths in the category “diseases, maternal and perinatal conditions and nutritional deficiencies” in France and Europe. Respiratory infections are the primary cause of death i
Safe & Easy Environment for Alzheimer’s disease and related disorders – SafEE
All over the world the increasing prevalence of chronic disorders and its impact on functional decline is challenging the sustainability of health care systems. Older individuals also frequently experience the reversible “frailty syndrome”, which overlaps with chronic diseases, increasing incidence
3D X-Ray and FTIR imaging for routine histopathology in chronic kidney disease – 3DXIR-Pathology
We propose the development of a new diagnostic strategy by image-guided biopsy using transmission X-Ray microscopy (TXM) and three-dimensional (3D) infrared (IR) imaging for combining the morphological and molecular/biochemical features of a pathological tissue. The application example for proof-of-
Predictive and patient-specific numerical simulations of endovascular interventions – ENDOSIM
Abdominal aortic aneurysm (AAA) is an asymptomatic disease which consists in abnormal enlargement of the aorta. Some criteria, like aneurysm diameter or peak wall stress, were developed to assess the growth of the aneurysm and its risk of rupture. If a criterion is met, two surgical procedures can b
Swallowing & Respiration : Modelling & e-Health at Home – e-SwallHome
The project Swallowing & Breathing: Modelling and e-Health at Home (e-SwallHome) aims to explain the normal behavior of two coupled functions in human, swallowing and breathing, to better understand the etiology of the mechanisms underlying pathological behaviors of dysphagia, dyspnea and dysphonia,
Terminologies and Ontologies for Linking Billing Information and Accurate Clinical data – TOLBIAC
Activity based funding is an essential part of hospital management. Diagnosis Related Groups (DRGs) is the best-known classification system that is used in this funding model. Such model was adapted in France within the PMSI (Programme de Médicalisation des Systèmes d’information) that takes into ac
Interpenetrated Fibrin scaffolds for the construction of Human Skin Equivalents for full thickness burns – FibriDerm
The FibriDerm project aims at the development and usage of fibrin-based biomaterials, with mechanical properties adapted to new applications. These materials, elaborated from interpenetrated networks of polymers, are self-supported and not retractable; these properties open new fields of application
In search of Fast Oscillations as Reliable markers of Cognition and Epilepsy – FORCE
Nearly 35% of epileptic patients do not respond to antiepileptic drugs, one fourth of whom can benefit from resective surgery. This represents in Europe around 250 000 patients. The identification of the cortical areas to be removed (the Epileptogenic Zone, EZ), and the evaluation of their functiona
Optimizing the management of patients in hospital – ClinMine
An increasing number of hospital data is nowadays available. In France, each hospital has data Medicalization Program Information Systems (PMSI) and most of hospitals rely on software to manage their drug prescriptions or test results, including biology. Many studies are emerging to exploit these da
Navigated OCT – NOCT
The current biopsy procedure is to introduce a needle inside the patient towards a given target using echography imaging for control of the position. Reaching the target at the right position is a real issue for diagnosis, therapy and also prognosis, for example concerning tumors or abscess. The
Intraoperative assessment of liver function by near-infrared fluorescent camera in liver surgery – iFLOW
The liver has a remarkable capability to regenerate. A healthy human liver can regenerate more than 2/3 of its mass. However, patients undergoing liver surgery often suffer from liver diseases accompanied by a significant reduction in liver function and regenerative capacity. Post-operative liver f
Non Invasive Monitoring Of PIC (Intracranial Pressure) – NIM-O-PIC
The coordinating partner of this project invented and patented several methods allowing changes in intracranial pressure (ICP) to be measured noninvasively through the ear. These methods are based upon the concept that ICP changes are transmitted, within a few tens of seconds, to the inner ear fluid
Mobility assessment and follow-up in frail elderly : clinico technical validation of a smart insole in real life – RESPECT
The RESPECT project is aimed at validating an instrument for supporting physical activity and monitor multiple parameters of frailty (a pre-disability condition) in older persons. The device consists of a smart, removable, energetically autonomous insole. It measures dynamic characteristics of gait
Design of medical devices in textiles optimized for gynecological surgery. Application for the treatment of female genital prolapse – PELVINOV
The aim of this collaboration is to produce textile reinforcement implants for the treatment of genital prolapse. Existing devices are currently not very deformable. These implants are indeed derived from those used in surgery (hernia) and have not been specifically developed, especially on their me