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Starting the PlanEt Formation by Early Dust Growth – SEED
The frequent detection of exo-planets around nearby stars has opened up a new field for astrophysical research to study exciting planetary worlds outside our solar system. In the formation process of these planets, small dust particles mainly made of silicate and carbon are the main ingredient to fo
Ambiguity in Markets and Social Interactions: Theory and Applications – AMSI
Most economic environments are characterized by uncertainty. Economic agents thus have to make decisions, the consequences of which cannot be known ex ante. Decision theory studies this process of decision making and tries to identify how the description of uncertainty influences beliefs, and throug
The importance of transcription-associated R-loops for chromosome condensation – TRACC
Condensin displays a high affinity for single-stranded DNA (ssDNA) in vitro. The localization of condensin at highly expressed genes in vivo strongly suggest that gene transcription produces the ssDNA that is recognized by condensin. The exact origin of this ssDNA remains unclear however. Based on o
Novel Iron-based catalysts for fuel cells – CAFERINNO
Today, our energy needs are in large part fulfilled by fossil fuels. Tomorrow, renewable energy sources will play an ever increasing role. For the transportation sector, a renewable fuel will be necessary, except for electric vehicles powered by rechargeable batteries, but having a restricted drivin
Ecological en evolutionary determinants of diversification: integrating biogeography, functional ecology, and macroevolution – ECOEVOBIO
The ECOEVOBIO projects aim to identify the ecological traits and environmental variables that affect rates of molecular evolution, speciation and extinction. This will allow us to answer fundamental questions in ecology and evolution: how does latitude, environmental variables correlated with latitu
High resolution sequence based dissection of genomic intervals controlling resistance to Sharka disease and chilling requirement in stone fruit trees – ABRIWG
We address these challenges by capitalizing on genomics/genetics data in key Prunus species, rich germplasm resources, innovative genotyping by whole genome sequencing for marker assisted breeding strategies to accelerate improvement of varieties: A) in the short term for genes controlling resistanc
Structural characterization of protein states involved in Huntington’s disease by integrative approaches – SPIN-HD
Huntington’s disease (HD) is a rare and lethal neurodegenerative pathology caused by mutation of the gene huntingtin that results in a protein with an expanded tract of glutamines (PolyGln). Individuals with glutamine tracts larger than 35 in the N-terminal region of huntingtin (N-Htt) have a high p
NuAGES -- a New cloud Architecture for General Extraction Services. – NuAGES
The Internet Memory Research foundation in Paris is home to Europe's most sophisticated web archiving technology. On the other side of La Manche the applicant's team at the University of Sheffield develop a world-leading infrastructure for text processing -- GATE, a General Architecture for Text Eng
Optical combs for photonic waveform synthesiser and frequency control – PhotoSynth
Since the development of the laser, emulating the numerous breakthroughs achieved in electronics with optical waves has been a major goal in science and technology. This is the realm of photonics. Despite the huge progress made towards the fulfilment of the photonics “raison d’être” and its potentia
Multidomain Intervention to preveNt Disability in ElDers – MINDED
n the present project (Multidomain Intervention to preveNt Disability in ElDers, MINDED), we propose to conduct a pilot study aimed at estimating the effects of a multidomain person-tailored preventive intervention (based on physical activity, cognitive training, and nutritional modifications) on fr
Post-transcriptional Control of the Aire-Driven Expression of self-antigens in the Thymus – CADET
/ / / / Immune tolerance is key to the maintenance of the integrity of organisms against foreign invaders with respect to self-constituents. Deregulation of this mechanism promotes the occurrence of life-threatening autoimmune diseases that affect 5-10% of the general population. Previously, the pro