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Des cellules aux tissus: au croisement de la Physique et de la Biologie (CelTisPhyBio)


Action : Laboratoires d'excellence


N° de convention : 11-LABX-0038

Informations générales

  • Référence projet : 11-LABX-0038
  • RST : Bruno GOUD
  • Etablissement Coordinateur : Paris Sciences Lettres - Quartier Latin
  • Région du projet : Île-de-France
  • Discipline : 5 - Bio Med
  • Aide allouée : 7 000 550 €
  • Date de début du projet : 01/03/2012
  • Date de fin du projet : 31/12/2019
  • Site web du projet : www.labex-celtisphybio.fr
  • Mots clés : biologie cellulaire, physique, biophysique, membranes, fonctions cellulaires, communication cellulaire, multi échelle

Résumé du projet

The Labex CelTisPhyBio, coordinated by B. Goud and M. Dahan, is composed of 31 research teams and 2 platforms, belonging to five departments at the Institut Curie and one at ESPCI. The general goal of the Labex is to foster research at the physics-biology interface. The scientific strategy is a multiscale approach whereby knowledge of the properties of molecules in the cell is used as an input for studying the behavior of cells and the knowledge of the properties of cells is used as an input to study tissues. The Labex has been structured around three major reseach axis: (i) Dynamic Cell membrane modelling, (ii) Regulation of cellular functions  and (iii) Communication of cells with their microenvironment in normal tissue and cancer. The Labex has been successful in enabling new collaborative research, as well as the acquisition of state-of-the-art equipment. Several programs have been launched including a postdoctoral program, a project grant program, an international chair program, and in 2016 the Groundbreaking program, a new structuring program to foster collaborations and innovative projects. It has also provided unique training opportunities, including the support of international courses at the Institut Curie and the co-organization of the Cytoskeleton course and workshop with the training Unit of the Institut Curie. Outreach actions include the creation of a website and public communication of science via international media. The Labex CelTisPhyBio has several collaborations with other organizations within PSL (College de France, ENS, ESPCI, Labex DEEP). The scientific and structuring actions of the Labex are anchored in an international setting thanks to our close links with Weizmann Institute, MPI Dresden, MBI Singapore or EMBL. Building on these strengths, a major objective is now to promote exploitation of scientific results and to establish new partnerships with health industry worlwide.

(L'auteur de ce résumé est le coordinateur du projet, qui est responsable du contenu de ce résumé. L'ANR décline par conséquent toute responsabilité quant à son contenu.)